Robust Linear Trend Test for Low-Coverage Next-Generation Sequence Data Controlling for Covariates
نویسندگان
چکیده
منابع مشابه
Estimating optimal window size for analysis of low-coverage next-generation sequence data
MOTIVATION Current high-throughput sequencing has greatly transformed genome sequence analysis. In the context of very low-coverage sequencing (<0.1×), performing 'binning' or 'windowing' on mapped short sequences ('reads') is critical to extract genomic information of interest for further evaluation, such as copy-number alteration analysis. If the window size is too small, many windows will ex...
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ژورنال
عنوان ژورنال: Mathematics
سال: 2020
ISSN: 2227-7390
DOI: 10.3390/math8020217